(DOWNLOAD) "Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C-H Bonds" by Stacey L. McDonald # eBook PDF Kindle ePub Free
eBook details
- Title: Copper-Catalyzed Electrophilic Amination of sp2 and sp3 C-H Bonds
- Author : Stacey L. McDonald
- Release Date : January 18, 2016
- Genre: Chemistry,Books,Science & Nature,
- Pages : * pages
- Size : 2660 KB
Description
This thesis reports the latest developments in the direct amination of various C-H bonds using an H-Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines.
The material outlined in this book shows how McDonald achieved C-H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source.
McDonald’s findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.